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COVID-19 Pediatric

Evidence Based Medicine

The Nemours medical librarians and faculty are searching the literature to provide you with the best pediatric evidence based resources on COVID-19.  The freely available evidence based articles and guidance listed below are updated twice weekly.

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Redbook Online

KidsHealth from Nemours - Information to share with patients and families

Healthcare Toolbox - Resources for healthcare staff and families on managing the stress/psychological impact of COVID-19

COVID-19 Practice Management Resources

CME credit can be claimed for your search if you click on the CLAIM CME CREDIT link located at the top right side of this page.

Interactive Case Primer

COVID-19 Primer: Virtual Patient Simulation. An Interactive Case from NEJM Resident 360

* New * COVID-19 Vaccine: Frequently Asked Questions

MedEd on the Go: COVID-19 in Mothers and Infants

Anesthetic Complications Associated With Severe Acute Respiratory Syndrome Coronavirus 2 in Pediatric Patients

(18 minutes)

The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States

(29 minutes)

Testing:  Performance of RT-PCR on Saliva Specimens Compared With Nasopharyngeal Swabs for the Detection of SARS-CoV-2 in Children: A Prospective Comparative Clinical Trial

(14 minutes)

The Indirect Impact of the SARS-CoV-2 Pandemic on Invasive Group a Streptococcus, Streptococcus Pneumoniae and Staphylococcus Aureus Infections in Houston Area Children

(9 minutes)

Vaccines:  Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination in Pregnancy: Measures of Immunity and Placental Histopathology

(4 minutes)

Maternal Antibody Response, Neutralizing Potency, and Placental Antibody Transfer After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

(18 minutes)

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study

(28 minutes)

Monoclonal antibodies for the treatment of COVID-19 in a patient with high-risk acute leukaemia

(5 minutes)

MIS-C: Trends in Geographic and Temporal Distribution of US Children With Multisystem Inflammatory Syndrome During the COVID-19 Pandemic

(22 minutes)

Letter: Assessing Child Abuse Hotline Inquiries in the Wake of COVID-19: Answering the Call

(8 minutes)

Brief Communication: COVID-19 and maternal and perinatal outcomes

(5 minutes)

August 1, 2021

Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

(22 minutes)

Retinal nerve fibre layer and ganglion cell layer changes in children who recovered from COVID-19: a cohort study

(8 minutes)

COVID-19 in Pregnant Women and Their Newborn Infants

(11 minutes)

A Bayesian Model to Predict COVID-19 Severity in Children

(15 minutes)

Telemonitoring, Telemedicine and Time in Range During the Pandemic: Paradigm Change for Diabetes Risk Management in the Post-COVID Future

(39 minutes)

Trends in US Outpatient Antibiotic Prescriptions During the Coronavirus Disease 2019 Pandemic

(26 minutes)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Setting-specific Transmission Rates: A Systematic Review and Meta-analysis

(30 minutes)

Defining Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placentitis: A Report of 7 Cases with Confirmatory In Situ Hybridization, Distinct Histomorphologic Features, and Evidence of Complement Deposition

(59 minutes)

August 2, 2021

Review: Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues for a personalized dosage regimen

(27 minutes)

Testing: Accuracy of saliva and nasopharyngeal sampling for detection of SARS-CoV-2 in community screening: a multicentric cohort study

(23 minutes)

Visits for Possible COVID-19 in a Pediatric Primary Care Practice Early in the Pandemic

(16 minutes)

Hidden pandemic: COVID-19-related stress, SLC6A4 methylation, and infants' temperament at 3 months

(19 minutes)

Academic performance of K-12 students in an online-learning environment for mathematics increased during the shutdown of schools in wake of the COVID-19 pandemic

(32 minutes)

Editorial: COVID-19 in children: time for a new strategy

(5 minutes)

Editorial Perspective: Challenges of research focusing on child and adolescent mental health during the COVID-19 era: what studies are needed?

(11 minutes)

August 3, 2021

Highlighted Article: Covid-19: Most symptomatic children recover within a week, study finds

(4 minutes)

Vaccines: Parents' Intentions and Perceptions About COVID-19 Vaccination for Their Children: Results From a National Survey

(30 minutes)

Vaccines: Thromboembolism after COVID-19 vaccine in patients with preexisting thrombocytopenia

(15 minutes)

The effect of COVID-19 lockdowns on paediatric lower limb orthopaedic presentations

(17 minutes)

Case Report: The COVID trap: pediatric diagnostic errors in a pandemic world

(20 minutes)

August 4, 2021

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

(33 minutes)

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

(31 minutes)

Preterm birth is not associated with asymptomatic/mild SARS-CoV-2 infection per se: Pre-pregnancy state is what matters

(20 minutes)

SARS-CoV-2 infections in people with primary ciliary dyskinesia: neither frequent, nor particularly severe

(12 minutes)

Case Report: New onset ANCA-associated vasculitis in an adolescent during an acute COVID-19 infection: a case report

(13 minutes)

August 5, 2021

Vaccines: COVID-19 Vaccine Safety in Adolescents Aged 12-17 Years - United States, December 14, 2020-July 16, 2021

(15 minutes)

Vaccines: Effectiveness of SARS-CoV-2 mRNA Vaccines for Preventing Covid-19 Hospitalizations in the United States

(32 minutes)

Vaccines: Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum

(59 minutes)

COVID-19-Specific Suicidal Thoughts and Behaviors in Psychiatrically Hospitalized Adolescents

(20 minutes)

Short Communication: Maternal SARS-CoV-2 infection during pregnancy: possible impact on the infant

(15 minutes)

Editorial: Impact of the COVID-19 pandemic on child and adolescent mental health services

(10 minutes)

Vaccines/Letter to the Editor: Healthcare-associated Transmission of COVID-19 Among Thai Healthcare Personnel Who Receive 2 Doses of a COVID-19 Vaccine: A Call for Considering a Booster Dose

(8 minutes)

Vaccines/Letter to the Editor: Successful vertical transmission of SARS-CoV-2 antibodies after maternal vaccination

(4 minutes)

August 6, 2021

August 7, 2021

MIS-C: Skewed Cytokine Responses Rather Than the Magnitude of the Cytokine Storm May Drive Cardiac Dysfunction in Multisystem Inflammatory Syndrome in Children

(34 minutes)

Review: Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System

(43 minutes)

Vaccines: Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1

(71 minutes)

Vaccines: Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study

(39 minutes)

Comment: COVID-19: the turning point for gender equality

(9 minutes)

August 8, 2021

Latest updates

Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis

(28 minutes)

Few Canadian children and youth were meeting the 24-hour movement behaviour guidelines 6-months into the COVID-19 pandemic: Follow-up from a national study

(60 minutes)

Review: Jumping a Moving Train: SARS-CoV-2 Evolution in Real Time

(41 minutes)

Autoantibodies stabilize neutrophil extracellular traps in COVID-19

(17 minutes)

Testing: Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2

(28 minutes)

MIS-C/Case Report: Severe acute inflammatory myositis and rhabdomyolysis in paediatric SARS-CoV-2-associated MIS-C (multisystem inflammatory syndrome in children)

(10 minutes)

Letter to the Editor: Letter to the editor regarding Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

(8 minutes)

August 9, 2021

Latest updates

Inflammasome activation at the crux of severe COVID-19

(47 minutes)

Testing: Rapid, Large-Scale Wastewater Surveillance and Automated Reporting System Enable Early Detection of Nearly 85% of COVID-19 Cases on a University Campus

(25 minutes)

The Relationship Between Delivery and the PaO2/FiO2 ratio in COVID-19: A Cohort Study

(18 minutes)

Vaccines: Dominance of alpha and Iota variants in SARS-CoV-2 vaccine breakthrough infections in New York City

(29 minutes)

Vaccines: Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review

(29 minutes)

Vaccines/Brief Report: Association of Myocarditis With BNT162b2 Messenger RNA COVID-19 Vaccine in a Case Series of Children

(14 minutes)

August 10, 2021