Evidence Based Medicine
The Nemours medical librarians and faculty are searching the literature to provide you with the best pediatric evidence based resources on COVID-19. The freely available evidence based articles and guidance listed below are updated twice weekly.
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Healthcare Toolbox - Resources for healthcare staff and families on managing the stress/psychological impact of COVID-19
COVID-19 Practice Management Resources
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Interactive Case Primer
COVID-19 Primer: Virtual Patient Simulation. An Interactive Case from NEJM Resident 360
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COVID-19 Vaccine: Frequently Asked Questions
MedEd on the Go: COVID-19 in Mothers and Infants
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions
Disparities in COVID-19 Vaccination Status, Intent, and Perceived Access for Noninstitutionalized Adults, by Disability Status - National Immunization Survey Adult COVID Module, United States, May 30-June 26, 2021.
Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine.
Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19.
Acute Abdomen and Appendicitis in 1010 Pediatric Patients With COVID-19 or MIS-C: A Multinational Experience from Latin America.
Multisystem inflammatory syndrome in children: A complication of COVID-19.
Pediatric Rheumatologic Effects of COVID-19.
Factors associated with COVID-19 viral and antibody test positivity and assessment of test concordance: a retrospective cohort study using electronic health records from the USA.
Rapid antibody testing for SARS-CoV-2 vaccine response in pediatric healthcare workers.
Return to School:
Association Between K-12 School Mask Policies and School-Associated COVID-19 Outbreaks - Maricopa and Pima Counties, Arizona, July-August 2021.
Return to School:
Pediatric COVID-19 Cases in Counties With and Without School Mask Requirements - United States, July 1-September 4, 2021.
Review: Neurological Effects of COVID-19 in Children.
Association of Children's Physical Activity and Screen Time With Mental Health During the COVID-19 Pandemic.
What was the impact of the first wave of COVID-19 on the delivery of care to children and adults with congenital heart disease? A qualitative study using online forums.
Case Series: The impact of COVID-19 on idiopathic scoliosis referrals: cause for concern.
Virtual Telesimulation for Medical Students During the COVID-19 Pandemic.
/Letter to the Editor:
No One Will be Safe Until Our Children are Safe: Parent's Attitude Towards COVID-19 Childhood Immunization.
Letter to the Editor: Low incidence of COVID-19 severe complications in a large cohort of children with sickle cell disease: a protective role for basal interferon-1 activation?
October 1, 2021
Characterization of SARS-CoV-2 and common cold coronavirus-specific T cell responses in MIS-C and Kawasaki disease children.
Delineating phenotypes of Kawasaki disease and SARS-CoV-2-related inflammatory multisystem syndrome: a French study and literature review.
Seroprevalence and Clinical Outcomes of SARS-CoV-2 in Paediatric Patients with Rheumatic Disease.
Lower nasopharyngeal viral load in young SARS-CoV-2-positive subjects.
Role of Geographic Risk Factors in COVID-19 Epidemiology: Longitudinal Geospatial Analysis.
Maternal COVID-19 and neonatal hearing loss: a multicentric survey.
Young people's romantic relationships and sexual activity before and during the COVID-19 pandemic.
Research Letter: Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk.
/Letter to the Editor:
SARS-CoV-2 Vaccination and Solid Organ Transplant Patients: Data Needed to Inform Safety and Efficacy.
October 2, 2021
Sleep during COVID-19-related school lockdown, a longitudinal study among high school students.
Review: Exploring carer burden amongst those caring for a child or adolescent with an eating disorder during COVID-19.
Case Report: COVID-19 in pregnancy: placental pathological patterns and effect on perinatal outcome in five cases.
The importance of influenza vaccination during the COVID-19 pandemic.
October 3, 2021
Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Influenza and RSV incidence during COVID-19 pandemic-an observational study from in-hospital point-of-care testing.
Future Directions for Vaccinating Children against the American Endemic: Treating Racism as a Virus.
Perspective: Putting the youngest among us into the nutrition "call for action" for food fortification strategies.
October 4, 2021
Acute Paediatric Mastoiditis in the UK Before and During the COVID-19 Pandemic: A National Observational Study.
Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity.
SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19.
Return to School:
Is Symptom Screening Useful for Identifying COVID-19 Infection in School Settings? Georgia, USA.
Household Transmission of Severe Acute Respiratory Syndrome Coronavirus-2 in the United States.
Editorial: COVID-19-Related Submission Priorities From the Journal of the Pediatric Infectious Diseases Society.
October 5, 2021
Children's Psychological Reactions to the COVID-19 Pandemic.
Statewide Interventions and Coronavirus Disease 2019 Mortality in the United States: An Observational Study.
Family support on intensive care units during the COVID-19 pandemic: a qualitative evaluation study into experiences of relatives.
Off-Label Prescription of COVID-19 Vaccines in Children: Clinical, Ethical, and Legal Issues.
Bicycle injuries presenting to the emergency department during COVID-19 lockdown.
October 6, 2021
Attitudes About COVID-19 and Health (ATTACH): Online Survey and Mixed Methods Study.
Highlighted Article: COVID-19-Associated Orphanhood and Caregiver Death in the United States.
(1 hour 6 minutes)
SARS-CoV-2 RNAemia and clinical outcomes in children with COVID-19.
Weight Gain during the COVID-19 Pandemic in a High-Risk Cohort of Children in San Francisco, CA.
Masks, Empathy, and a Pediatric Cancer Diagnosis During COVID-19.
COVID-19 and Routine Childhood Vaccinations-Identifying Gaps and Informing Solutions.
Letter: COVID-19 outbreak in children and/or adolescents.
October 7, 2021
Highlighted Article: COVID-19 Outbreaks at Youth Summer Camps - Louisiana, June-July 2021.
Highlighted Article: Multicomponent Strategies to Prevent SARS-CoV-2 Transmission - Nine Overnight Youth Summer Camps, United States, June-August 2021.
Prescription of anxiolytics, sedatives, hypnotics and antidepressants in outpatient, universal care during the COVID-19 pandemic in Portugal: a nationwide, interrupted time-series approach.
COVID-19 Vaccination for Caregivers in the Pediatric Medical Home: A Call to Action to Improve Community Vaccination Rates.
Editorial: If Young Children's Risk of SARS-CoV-2 Infection Is Similar to That of Adults, Can Children Also Contribute to Household Transmission?
Call for a universal PIMS-TS/MIS-C case definition.
October 8, 2021