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COVID-19 Pediatric

Evidence Based Medicine

The Nemours medical librarians and faculty are searching the literature to provide you with the best pediatric evidence based resources on COVID-19.  The freely available evidence based articles and guidance listed below are updated twice weekly.

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Redbook Online

KidsHealth from Nemours - Information to share with patients and families

Healthcare Toolbox - Resources for healthcare staff and families on managing the stress/psychological impact of COVID-19

COVID-19 Practice Management Resources

CME credit can be claimed for your search if you click on the CLAIM CME CREDIT link located at the top right side of this page.

Interactive Case Primer

COVID-19 Primer: Virtual Patient Simulation. An Interactive Case from NEJM Resident 360

Brief Report: Fecal-Oral Transmission of SARS-CoV-2 In Children is it Time to Change Our Approach?

(6 minutes)

Brief Report: The Early Experiences of a Single Tertiary Italian Emergency Department Treating COVID-19 in Children

(7 minutes)

Viewpoint: National Active Surveillance to Understand and Inform Neonatal Care in COVID-19

(8 minutes)

Commentary: Supporting Adolescents and Young Adults Exposed to or Experiencing Violence During the COVID-19 Pandemic

(11 minutes)

Commentary: Recognising and Addressing the Impact of COVID-19 on Obsessive-Compulsive Disorder

(5 minutes)

Letter: Children With Cancer in the Time of COVID-19: An 8-week Report From the Six Pediatric Onco-Hematology Centers in Lombardia, Italy

(6 minutes)

*MIS-C article* Case Report: Special Dermatological Presentation of Paediatric Multisystem Inflammatory Syndrome Related to COVID-19: Erythema Multiforme

(4 minutes)

July 1, 2020

Highlighted Article: Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With The Guidelines - Resuscitation Adult and Pediatric Task Forces of the American Heart Association

(15 minutes)

Practice Update: Non-Elective Pediatric Cardiac Catheterization During COVID-19 Pandemic: A New York Center Experience. (Free HTML, register for PDF)

(9 minutes)

*MIS-C article* Neurologic and Radiographic Findings Associated With COVID-19 Infection in Children

(13 minutes)

The Impact of Imposed Delay in Elective Pediatric Neurosurgery: An Informed Hierarchy of Need in the Time of Mass Casualty Crisis

(24 minutes)

Updated Diagnosis, Treatment and Prevention of COVID-19 in Children: Experts' Consensus Statement (Condensed Version of the Second Edition)

(17 minutes)

Case Report: SARS-CoV-2 Infection in Patients With Down Syndrome, Congenital Heart Disease, and Pulmonary Hypertension: Is Down Syndrome a Risk Factor?

(8 minutes)

Case Report: 4-month-old Boy Coinfected With COVID-19 and Adenovirus

(10 minutes)

*MIS-C article* Letter: Covid-19 in Peru: From Supervised Walks for Children to the First Case of Kawasaki-like Syndrome

(5 minutes)

July 2, 2020

Outcomes of a Rapid Adolescent Telehealth Scale-Up During the COVID-19 Pandemic

(21 minutes)

Child Poverty, Food Insecurity, and Respiratory Health During the COVID-19 Pandemic

(5 minutes)

Case Report: Cardiac Dysfunction and Thrombocytopenia-Associated Multiple Organ Failure Inflammation Phenotype in a Severe Paediatric Case of COVID-19

(7 minutes)

Editorial: Prioritising Children's Rights in the COVID-19 Response

(6 minutes)

Editorial: Prioritising Paediatric Surveillance During the COVID-19 Pandemic

(10 minutes)

*MIS-C article* Viewpoint: Is It Kawasaki Shock Syndrome, Kawasaki-like Disease or Pediatric Inflammatory Multisystem Disease? The Importance of Semantic in the Era of COVID-19 Pandemic

(13 minutes)

Letter: Finding Ordinary Magic in Extraordinary Times: Child and Adolescent Resilience During the COVID-19 Pandemic

(5 minutes)

July 3, 2020

Viewpoint: School closure, COVID ‐19 and lunch programme: Unprecedented undernutrition crisis in low‐middle income countries

(12 minutes)

Comment: Asymptomatic Case of Covid-19 in an Infant with Cystic Fibrosis

(3 minutes)

Letter: Spotlight on Child Abuse and Neglect Response in the Time of COVID-19

(3 minutes)

Letter: Rise in the Incidence of Abusive Head Trauma During the COVID-19 Pandemic

(5 minutes)

Letter: Will children reveal their secret? The coronavirus dilemma

(6 minutes)

Letter: Indirect effects of COVID-19 on child health care: delayed diagnosis of developmental dysplasia of the hip

(4 minutes)

July 4, 2020

*MIS-C article* Emergence of Kawasaki disease related to SARS-CoV-2 infection in an epicentre of the French COVID-19 epidemic: a time-series analysis

(19 minutes)

Limiting hospital resources for acute appendicitis in children: Lessons learned from the U.S. epicenter of the COVID-19 pandemic

(13 minutes)

*MIS-C article* Commentary: Multisystem Inflammatory Syndrome in Children in COVID-19 Pandemic

(7 minutes)

Letter: COVID-19 and child and adolescent psychiatry: an unexpected blessing for part of our population?

(6 minutes)

July 5, 2020

Practice Update: Management strategies for children with COVID-19: ESPR practical recommendations​

(26 minutes)

*MIS-C article* Gastrointestinal involvements in children with COVID-related multisystem inflammatory syndrome

(7 minutes)

Adolescent psychiatric disorders during the COVID-19 pandemic and lockdown

(24 minutes)

*MIS-C article* Case Report: Coronary artery dilatation in a child with hyperinflammatory syndrome with SARS-CoV-2-positive serology

(4 minutes)

*MIS-C article* Commentary: Kawasaki disease in the COVID-19 era: a distinct clinical phenotype?

(6 minutes)

Commentary: Rapid Testing of Healthcare Employees for COVID-19: What Can We Learn from the Seattle Experience?

(10 minutes)

Letter: The impact of social distancing on pediatric neurosurgical emergency referrals during the COVID-19 pandemic: a prospective observational cohort study

(5 minutes)

July 6, 2020

Practice Update: Evaluation and Follow-Up of Pediatric COVID-19 in Terms of Cardiac Involvement: A Scientific Statement From the Association of Turkish Pediatric Cardiology and Pediatric Cardiac Surgery

(20 minutes)

Multicenter Study: Characterisation of COVID-19 Pandemic in Paediatric Age Group: A Systematic Review and Meta-Analysis

(21 minutes)

Severe and Fatal Forms of COVID-19 in Children

(11 minutes)

COVID-19 Pandemic: Perspective from Italian Pediatric Emergency Physicians

(16 minutes)

Pills to think about in allergic rhinitis children during COVID‐19 era

(5 minutes)

Case Report: A Teenager with Congenital Heart Defect and Covid-19

(6 minutes)

Perspective: Zooming Toward a Telehealth Solution for Vulnerable Children With Obesity During Coronavirus Disease 2019

(5 minutes)

Letter: COVID-19 in pediatric patients: What the prehospital teams need to know

(5 minutes)

July 7, 2020

Highlighted Article: European Consensus Recommendations for Neonatal and Paediatric Retrievals of Positive or Suspected COVID-19 Patients

(25 minutes)

The clinical course of SARS-CoV-2 positive neonates

(14 minutes)

COVID-19 PICU Guidelines: For High- And Limited-Resource Settings

(50 minutes)

*MIS-C article* Case Report: COVID-19 Associated Kawasaki-like Multisystem Inflammatory Disease in an Adult

(6 minutes)

Case Report: Household Transmission of SARS-CoV-2 from Adults to Children

(9 minutes)

Letter: Coronavirus disease 2019 3 months after hematopoietic stem cell transplant: A pediatric case report

(4 minutes)

Letter: At home dose escalation of Propranolol for Infantile Hemangiomas during the COVID ‐19 Pandemic

(6 minutes)

July 8, 2020

Implementation of Home-Based Telemental Health in a Large Child Psychiatry Department During the COVID-19 Crisis

(19 minutes)

Nemours author alert: (Dr. Tushar Chandra, Radiology, NCH):

 A Primer for Pediatric Radiologists on Infection Control in an Era of COVID-19

(30 minutes)

Brief Report: SARS-CoV-2 Infection in Spanish Children with Chronic Kidney Pathologies

(9 minutes)

*MIS-C article* A Viral Infection Explanation for Kawasaki Disease in General and for COVID-19 Virus-Related Kawasaki Disease Symptoms

(9 minutes)

*MIS-C article* Pediatric Inflammatory Mulitsyste, Syndrome with Central Nervous System Involvement and Hypocomplementemia Following SARS-CoV-2 Infection

(5 minutes)

Case Report: Myocarditis in a 16-year-old Boy Positive for SARS-CoV-2

(4 minutes)

*MIS-C article* Case Report: Hyperinflammatory Shock Related to COVID-19 in a Patient Presenting With Multisystem Inflammatory Syndrome in Children: First Case from Iran

(7 minutes)

Clinical Features of Critical Coronavirus Disease 2019 in Children

(9 minutes)

Opinion: Health-education to prevent COVID-19 in schoolchildren: a call to action

(9 minutes)

Letter: The Value of Chest CT as a COVID-19 Screening Tool in Children

(8 minutes)

July 9, 2020

Provision of Pediatric Immunization Services During the COVID-19 Pandemic: an Assessment of Capacity Among Pediatric Immunization Providers Participating in the Vaccines for Children Program — United States, May 2020

(12 minutes)

Practice Update: Cardiopulmonary Considerations for High School Student-Athletes During the COVID-19 Pandemic: NFHS-MSSM Guidance Statement

(7 minutes)

Application and Preliminary Outcomes of Remote Diagnosis and Treatment During the COVID-19 Outbreak: Retrospective Cohort Study

(18 minutes)

Case Series: SARS-CoV-2 Infection in Febrile Neonates

(17 minutes)

Case Report: Rhabdomyolysis and Acute Renal Failure in an Adolescent with COVID-19

(9 minutes)

July 10, 2020

Highlighted Article: Should Pediatric Patients Be Prioritized When Rationing Life-Saving Treatments During the COVID-19 Pandemic?

(27 minutes)

The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs

(20 minutes)

COVID-19 Epidemic: Clinical Characteristics of Patients in Pediatric Isolation Ward

(11 minutes)

Chilblains in children in the setting of COVID‐19 pandemic

(10 minutes)

Case Report: Erythema multiforme-like lesions in children and COVID-19

(6 minutes)

Case Report: Chilblain-like lesions in children following suspected COVID-19 infection

(6 minutes)

July 11, 2020

Practice Update: CHEST Reviews: Addressing reduced laboratory-based pulmonary function testing during a pandemic

(32 minutes)

Guillain-Barre Syndrome Associated with SARS-CoV-2 Detection and a COVID-19 Infection in a Child

(11 minutes)

Operationalizing an Academic Pediatric Practice during the COVID-19 Crisis

(8 minutes)

Extrapulmonary manifestations of COVID-19

(54 minutes)

Clinical characteristics and outcome of SARS-CoV-2 infection in Italian pediatric oncology patients: a study from the Infectious Diseases Working Group of the AIEOP

(17 minutes)

A call to action to address COVID-19–induced global food insecurity to prevent hunger, malnutrition, and eating pathology

(7 minutes)

Letter: Telemedicine for management of paediatric infectious diseases during COVID-19 outbreak

(4 minutes)

July 12, 2020

*MIS-C article* Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study

(22 minutes)

Thromboinflammation in COVID-19 acute lung injury

(16 minutes)

Case Report: Guillain–Barré Syndrome Associated with SARS-CoV-2 Infection in a Pediatric Patient

(9 minutes)

July 13, 2020

Disproportionate impact of the COVID-19 pandemic on immigrant communities in the United States

(15 minutes)

Nemours author alert: (Dr. Sharon M. Weinberger, Cardiology, AIDHC): 

Telehealth for Pediatric Cardiology Practitioners in the Time of COVID-19

(29 minutes)

Challenges of COVID-19 in children in low- and middle-income countries

(15 minutes)

Exploring the young demographic profile of COVID-19 cases in Hong Kong: Evidence from migration and travel history data

(23 minutes)

Brief Report: Intrauterine Transmission of SARS-CoV-2 Infection in a Preterm Infant

(11 minutes)

Instructive Case: Probable Vertical Transmission of SARS-CoV-2 Infection

(14 minutes)

Commentary: SARS-COV-2 Maternal-Child Transmission: Can It Occur Before Delivery and How Do We Prove It?

(9 minutes)

Case Report: Clinical and Imaging Features of COVID-19 in a Neonate

(6 minutes)

July 14, 2020

Hot Topic: Transplacental transmission of SARS-CoV-2 infection

(15 minutes)

Practice Update: Acute Kidney Injury and Special Considerations during Renal Replacement Therapy in Children with Coronavirus Disease-19: Perspective from the Critical Care Nephrology Section of the European Society of Paediatric and Neonatal Intensive Care

(28 minutes)

Neurological Involvement in COVID-19 and Potential Mechanisms: A Review

(26 minutes)

COVID-19 Disease Severity Risk Factors for Pediatric Patients in Italy

(28 minutes)

Prevention and control measures for neonatal COVID-19 infection: a scoping review

(26 minutes)

Viewpoint: Paediatric ethical issues during the COVID-19 pandemic are not just about ventilator triage

(7 minutes)

Comment: COVID-19 in a pediatric heart transplant recipient: Emergence of donor-specific antibodies

(4 minutes)

Letter: COVID‐19 in a child with tuberculous airway compression

(5 minutes)

July 15, 2020

Practice Update: Care Delivery for Children with Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians

(21 minutes)

Compliance with infection control rules among adolescents in Oslo during the COVID-19 pandemic

(11 minutes)

Using the prone position could help to combat the development of fast hypoxia in some patients with COVID‐19

(11 minutes)

Case Report: Anterior wall myocardial infarction in a 16-year-old man caused by coronary artery aneurysm during the outbreak of COVID-19

(8 minutes)

Insights: Family separation during COVID-19

(5 minutes)

Ethics Rounds: Pediatric Palliative Care in a Pandemic: Role Obligations, Moral Distress, and the Care You Can Give

(16 minutes)

Comment: What do differences in case fatality ratios between children and adults tell us about COVID-19?

(5 minutes)

July 16, 2020

Nemours author alert: (Ann E. Kazak, PhD, Director, Nemours Center for Healthcare Delivery Science, AIDHC): 

Psychology is an essential science: American Psychologist highlights the role of psychology in understanding and addressing COVID-19

(5 minutes)

COVID-19: minimising contaminated aerosol spreading during CPAP treatment

(9 minutes)

Mild SARS-CoV-2 infections in children might be based on evolutionary biology and linked with host reactive oxidative stress and antioxidant capabilities

(14 minutes)

Case Report: SARS-CoV-2 Infection and Thrombosis: Phlegmasia Cerulea Dolens Presenting with Venous Gangrene in a Child

(13 minutes)

Reflections: Vulnerable Children in a Dual Epidemic

(6 minutes)

Debate: Lessons learned in lockdown – a one‐day remotely delivered training on low‐intensity psychological interventions for common mental health conditions

(7 minutes)

*MIS-C article* Letter: Insights into pediatric multi-system inflammatory syndrome and COVID-19

(7 minutes)

July 17, 2020

Highlighted Article: A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children​

(32 minutes)

Child Care in the Time of COVID-19: A Period of Challenge and Opportunity

(25 minutes)

Cardiac workup and monitoring in hospitalised children with COVID- 19

(12 minutes)

Considerations and Future Directions for Conducting Clinical Research with Pediatric Populations During the COVID-19 Pandemic

(12 minutes)

Peer Influence in Adolescence: Public-Health Implications for COVID-19

(9 minutes)

After the First Wave of COVID-19: Reflections from Italy

(8 minutes)

Perspective: Trauma Does not Quarantine: Violence During the COVID-19 Pandemic

(6 minutes)

*MIS-C article* Letter: Cytokine Profile in an Adolescent With Pediatric Multisystem Inflammatory Syndrome Temporally Related to COVID-19

(5 minutes)

Letter: Central Apnea in an Adolescent With COVID-19

(5 minutes)

Latest updates

July 18, 2020